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module-whatis	        "3D reconstructions or 2D class averages in electron cryo-microscopy (cryo-EM)"
module-url		""
module-license	        "GPLv2 license"
module-maintainer	"Spencer Bliven <>"

module-help	"
RELION (for REgularised LIkelihood OptimisatioN, pronounce rely-on) is a
stand-alone computer program that employs an empirical Bayesian approach to
refinement of (multiple) 3D reconstructions or 2D class averages in electron
cryo-microscopy (cryo-EM). It is developed in the group of Sjors Scheres at the
MRC Laboratory of Molecular Biology. Briefly, the ill-posed problem of
3D-reconstruction is regularised by incorporating prior knowledge: the fact
that macromolecular structures are smooth, i.e. they have limited power in the
Fourier domain. In the corresponding Bayesian framework, many parameters of a
statistical model are learned from the data, which leads to objective and
high-quality results without the need for user expertise. The underlying theory
is given in Scheres (2012) JMB. A more detailed description of its
implementation is given in Scheres (2012) JSB. If RELION is useful in your
work, please cite at least one of these papers. 

Scheres(2012) JMB
Scheres(2012) JSB